Jean-Paul Desaulniers : rechercher sur Z-Library

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1

Evaluation of siRNAs that contain internal variable-length spacer linkages

Tim C. Efthymiou, Brandon Peel, Vanthi Huynh, Jean-Paul Desaulniers

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2012

Langue:

english

Fichier:

PDF, 1.89 MB

english, 2012

2

siRNAzos: A New Class of Azobenzene-Containing siRNAs that Can Photochemically Regulate Gene Expression

Hammill, Matthew L., Isaacs-Trépanier, Cameron, Desaulniers, Jean-Paul

Journal:

ChemistrySelect

Année:

2017

Langue:

english

Fichier:

PDF, 1.07 MB

english, 2017

3

Synthesis of Helix 69 of Escherichia coli 23S rRNA Containing Its Natural Modified Nucleosides, m3Ψ and Ψ.

Helen M.-P. Chui, Jean-Paul Desaulniers, Stephen A. Scaringe, Christine S. Chow

Journal:

Année:

2003

Fichier:

PDF, 60 KB

2003

4

ChemInform Abstract: Synthesis and Properties of Oligonucleotides that Contain a Triazole-Linked Nucleic Acid Dimer (IV).

Tim C. Efthymiou, Jean-Paul Desaulniers

Journal:

Année:

2011

Fichier:

PDF, 30 KB

2011

5

Synthesis and properties of oligonucleotides that contain a triazole-linked nucleic acid dimer

Tim C. Efthymiou, Jean-Paul Desaulniers

Journal:

Journal of Heterocyclic Chemistry

Année:

2011

Langue:

english

Fichier:

PDF, 188 KB

english, 2011

6

NMR conformational analysis of p-tolyl furanopyrimidine 2′-deoxyribonucleoside and crystal structure of its 3′,5′-di-O-acetyl derivative

Noor Esho, Jean-Paul Desaulniers, Brian Davies, Helen M.-P. Chui, Meneni Srinivasa Rao, Christine S. Chow, Slawomir Szafert, Roman Dembinski

Journal:

Bioorganic & Medicinal Chemistry

Année:

2005

Langue:

english

Fichier:

PDF, 411 KB

english, 2005

7

Solution conformations of two naturally occurring RNA nucleosides: 3-Methyluridine and 3-methylpseudouridine

Jean-Paul Desaulniers, Helen M.-P. Chui, Christine S. Chow

Journal:

Bioorganic & Medicinal Chemistry

Année:

2005

Langue:

english

Fichier:

PDF, 158 KB

english, 2005

8

Expanding the repertoire of small molecule transcriptional activation domains

Ryan J. Casey, Jean-Paul Desaulniers, Jonas W. Hojfeldt, Anna K. Mapp

Journal:

Bioorganic & Medicinal Chemistry

Année:

2009

Langue:

english

Fichier:

PDF, 289 KB

english, 2009

9

Inhibition of ErbB2(Her2) expression with small molecule transcription factor mimics

Lori W. Lee, Christopher E.C. Taylor, Jean-Paul Desaulniers, Manchao Zhang, Jonas W. Højfeldt, Quintin Pan, Anna K. Mapp

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2009

Langue:

english

Fichier:

PDF, 414 KB

english, 2009

10

Efficient synthesis and cell-based silencing activity of siRNAS that contain triazole backbone linkages

Tim C. Efthymiou, Vanthi Huynh, Jaymie Oentoro, Brandon Peel, Jean-Paul Desaulniers

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2012

Langue:

english

Fichier:

PDF, 821 KB

english, 2012

11

Sheep red blood cells armed with anti-CD20 single-chain variable fragments (scFvs) fused to a glycosylphosphatidylinositol (GPI) anchor: a strategy to target CD20-positive tumor cells

Nayera Hamdy, Anton Scott Goustin, Jean-Paul Desaulniers, Mei Li, Christine S. Chow, Ayad Al-Katib

Journal:

Journal of Immunological Methods

Année:

2005

Langue:

english

Fichier:

PDF, 2.20 MB

english, 2005

12

Pseudouridines in rRNA helix 69 play a role in loop stacking interactions

Desaulniers, Jean-Paul, Chang, Yu-Cheng, Aduri, Raviprasad, Abeysirigunawardena, Sanjaya C., SantaLucia, Jr., John, Chow, Christine S.

Journal:

Organic & Biomolecular Chemistry

Année:

2008

Langue:

english

Fichier:

PDF, 136 KB

english, 2008

13

Synthesis and Properties of RNAs that Contain A Pna-Rna Dimer

Gong, Wei, Desaulniers, Jean-Paul

Journal:

Nucleosides Nucleotides & Nucleic Acids

Année:

2012

Langue:

english

Fichier:

PDF, 361 KB

english, 2012

14

Gene-silencing properties of siRNAs that contain internal amide-bond linkages

Gong, Wei, Desaulniers, Jean-Paul

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2012

Langue:

english

Fichier:

PDF, 983 KB

english, 2012

15

Inter-year repeatability study of volatile organic compounds from surface decomposition of human analogues

Stadler, Sonja, Desaulniers, Jean-Paul, Forbes, Shari L.

Journal:

International Journal of Legal Medicine

Année:

2015

Langue:

english

Fichier:

PDF, 943 KB

english, 2015

16

Synthesis of Helix 69 of Escherichia c oli 23S rRNA Containing Its Natural Modified Nucleosides, m 3 Ψ and Ψ

Chui, Helen M.-P., Desaulniers, Jean-Paul, Scaringe, Stephen A., Chow, Christine S.

Journal:

Journal of Organic Chemistry

Année:

2002

Langue:

english

Fichier:

PDF, 140 KB

english, 2002

17

Synthesis of 15 N-Enriched Pseudouridine Derivatives

Desaulniers, Jean-Paul, Ksebati, Bashar, Chow, Christine S.

Journal:

Organic Letters

Année:

2003

Langue:

english

Fichier:

PDF, 84 KB

english, 2003

18

New decomposition stages to describe scenarios involving the partial and complete exclusion of insects

Comstock, Jenna L., Desaulniers, Jean-Paul, LeBlanc, Hélène N., Forbes, Shari L.

Journal:

Canadian Society of Forensic Science Journal

Année:

2015

Langue:

english

Fichier:

PDF, 1.03 MB

english, 2015

19

Conjugation and Evaluation of Small Hydrophobic Molecules to Triazole-Linked siRNAs

Peel, Brandon J., Hagen, Gordon, Krishnamurthy, Kalaivani, Desaulniers, Jean-Paul

Journal:

ACS Medicinal Chemistry Letters

Année:

2015

Langue:

english

Fichier:

PDF, 1.19 MB

english, 2015

20

Encyclopedia of Reagents for Organic Synthesis || Tris(2-acetoxyethoxy)orthoformate

Desaulniers, Jean-Paul

Année:

2001

Langue:

english

Fichier:

PDF, 83 KB

english, 2001

21

Encyclopedia of Reagents for Organic Synthesis || Pivaloxymethyl chloride

Desaulniers, Jean-Paul

Année:

2001

Langue:

english

Fichier:

PDF, 63 KB

english, 2001

22

Synthesis and in vitro assessment of chemically modified siRNAs targeting BCL2 that contain 2′-ribose and triazole-linked backbone modifications

Hagen, Gordon, Peel, Brandon J., Samis, John, Desaulniers, Jean-Paul

Journal:

Année:

2015

Langue:

english

Fichier:

PDF, 1.89 MB

english, 2015

23

A molecular characterization of the agonist binding site of a nematode cys-loop GABA receptor

Kaji, Mark D, Kwaka, Ariel, Callanan, Micah K, Nusrat, Humza, Desaulniers, Jean-Paul, Forrester, Sean G

Journal:

British Journal of Pharmacology

Année:

2015

Langue:

english

Fichier:

PDF, 1.26 MB

english, 2015

24

Chemical Architecture and Applications of Nucleic Acid Derivatives Containing 1,2,3-Triazole Functionalities Synthesized via Click Chemistry

Efthymiou, Tim, Gong, Wei, Desaulniers, Jean-Paul

Journal:

Année:

2012

Langue:

english

Fichier:

PDF, 784 KB

english, 2012

25

Effective gene-silencing of siRNAs that contain functionalized spacer linkages within the central region

Desaulniers, Jean-Paul, Hagen, Gordon, Anderson, Jocelyn, McKim, Chris, Roberts, Blake

Journal:

Année:

2017

Langue:

english

Fichier:

PDF, 492 KB

english, 2017

26

Efficient synthesis of the GABA A receptor agonist trans-4-aminocrotonic acid (TACA)

Forrester, Sean, Foster, Joshua, Robert, Sebastien, Salim, Lidya, Desaulniers, Jean-Paul

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2017

Langue:

english

Fichier:

PDF, 301 KB

english, 2017

27

Effective carrier-free gene-silencing activity of cholesterol-modified siRNAs

Salim, Lidya, McKim, Chris, Desaulniers, Jean-Paul

Journal:

Année:

2018

Langue:

english

Fichier:

PDF, 453 KB

english, 2018

28

Stability and evaluation of siRNAs labeled at the sense strand with a 3′-azobenzene unit

Hammill, Matthew L., Patel, Ayushi, Alla, Maria Abd, Desaulniers, Jean-Paul

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2018

Langue:

english

Fichier:

PDF, 899 KB

english, 2018

29

Targeted delivery and enhanced gene-silencing activity of centrally modified folic acid–siRNA conjugates

Salim, Lidya, Islam, Golam, Desaulniers, Jean-Paul

Journal:

Nucleic Acids Research

Année:

2019

Fichier:

PDF, 3.22 MB

2019

30

Effects of Chemical Modifications on siRNA Strand Selection in Mammalian Cells

Varley, Andrew J., Hammill, Matthew L., Salim, Lidya, Desaulniers, Jean-Paul

Journal:

Nucleic Acid Therapeutics (Formerly Oligonucleotides)

Année:

2020

Langue:

english

Fichier:

PDF, 414 KB

english, 2020

31

Synthesis and Evaluation of Neutral Phosphate Triester Backbone-Modified siRNAs

Tsubaki, Kouta, Hammill, Matthew L., Varley, Andrew J., Kitamura, Mitsuru, Okauchi, Tatsuo, Desaulniers, Jean-Paul

Journal:

ACS Medicinal Chemistry Letters

Année:

2020

Fichier:

PDF, 1.68 MB

2020

32

Bromination of codeine and its derivatives: Revisiting a 95Â year old process

Barmaki, Samira, Ali, Arlene, Desaulniers, Jean-Paul, Bolshan, Yuri

Journal:

Tetrahedron Letters

Année:

2020

Fichier:

PDF, 415 KB

2020

33

To Conjugate or to Package? A Look at Targeted siRNA Delivery Through Folate Receptors

Salim, Lidya, Desaulniers, Jean-Paul

Journal:

Nucleic Acid Therapeutics (Formerly Oligonucleotides)

Année:

2020

Fichier:

PDF, 785 KB

2020